Fig. 4

The expression pattern and clinical characteristics of CASC18 in TCGA-TSCC cohort and CAL27

CASC18 is highly expressed in tumors as compared with A the normal tissues, B matched adjacent tissue in TCGA-TSCC cohort. CASC18 is C highly expressed in tumors derived from patients with OLNM as compared with those without OLNM, D positively correlated with TGFB2 expression, and E poor prognosis predictor. F The subcellular distribution of CASC18 was assessed by FISH staining in CAL27 cells, with the reference of 18 S and U6. G The abundance of CASC18 in nuclear and cytoplasmic RNA was determined and normalized against that of the internal control of 18 S and U6. Data are presented as mean ± SD, with a p-value < 0.05 considered statistically significant