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Fig. 3 | Molecular Medicine

Fig. 3

From: rAAV9‐mediated supplementation of miR-29b improve angiotensin-II induced renal fibrosis in mice

Fig. 3

Effects of rAAV9-miR-29b transduction on fibrotic changes in AngII-induced kidneys. A Representative Masson staining of kidney sections in each group quantitative analysis of fibrotic areas. Areas with positive blue staining show collagen fibers. Magnification, × 200. B Representative sirius red staining of kidney sections and quantitative analysis of fibrotic areas. Area with yellow stain show collagen type I (COL I) and green stain show collagen type III (COL III). Magnification, × 200. C Representative images of alpha-smooth muscle actin (a-SMA) immune staining of kidney among the groups(six high-power fields counted per group). Magnification, × 200. Values are mean ± SEM, n = 6. *P < 0.05 compared with control group. #P < 0.05 compared with rAAV9-negative control. Scale bar 100 μm

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