Skip to main content
Fig. 4 | Molecular Medicine

Fig. 4

From: rAAV9‐mediated supplementation of miR-29b improve angiotensin-II induced renal fibrosis in mice

Fig. 4

Effect of rAAV9-miR-29b delivery on fibrotic markers in kidney. Mature miR-29b levels was significantly increased in rAAV9-miR-29b transduction group. The expression levels of alpha-smooth muscle actin (a-SMA), collagen type I (COL I) and collagen type III (COL III) were evaluated as fold change relative to the control animals at 5 weeks post gene transfer. Values represent mean ± SEM (n = 6). Significance of differences: *P < 0.05, rAAV9-miR-29b vs. control group, #P < 0.05, AngII + rAAV9-miR-29b vs. rAAV9-negative control. rAAV9 indicates recombinant adeno-associated vector type 9; NC, negative control

Back to article page