Fig. 1From: CB2-mediated attenuation of nucleus pulposus degeneration via the amelioration of inflammation and oxidative stress in vivo and in vitroLow expression of CB2 was observed in both human and rat degenerative NP tissue. A Preoperative MRI of participants, who were divided into 4 groups (level: I, III, IV, V) according to the Pfirrmann classification. B Safranin O staining of participant NP tissues; scale bar, 1000 μm. C Representative specimens of immunohistochemical CB2 staining in the 4 separate groups (level: I, III, IV, and V) of participant NP tissues; scale bar, 100 μm. D Quantitative analysis of IHC staining of CB2 (*p < 0.05). E Representative MRI showing the signal intensity of IVD in rats. F H&E and safranin O staining, scale bar, 1000 μm. G Representative specimens of paraffin sections with IHC of CB2 in normal and IVDD rats. H Quantitative analysis of CB2 IHC staining (*p < 0.05). (n = 5 Independent experiments)Back to article page