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Fig. 2 | Molecular Medicine

Fig. 2

From: CB2-mediated attenuation of nucleus pulposus degeneration via the amelioration of inflammation and oxidative stress in vivo and in vitro

Fig. 2

H2O2 induces NPC degeneration and affects CB2 expression in NPCs. A CCK-8 results showing that cell viability is not affected by H2O2 at a concentration of 100 µM (*p < 0.05 compared with H2O2 100 µM, 12 h). B RT-qPCR results for aggrecan, collagen II, MMP3 and MMP13 (*p < 0.05). C Western blot results of collagen II, aggrecan, MMP3 and MMP13. D Representative ICC image of collagen II, aggrecan, MMP3 and MMP13; scale bar, 100 μm. E RT-qPCR results of CB2 at different time points after treatment (*p < 0.05). F Western blot results of CB2 at different time points after H2O2 treatment. G Quantitative analysis of the Western blot (* p < 0.05) (n = 3 Independent experiments)

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Molecular Medicine

ISSN: 1528-3658