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Fig. 2 | Molecular Medicine

Fig. 2

From: Human umbilical cord mesenchymal stem cells deliver exogenous miR-26a-5p via exosomes to inhibit nucleus pulposus cell pyroptosis through METTL14/NLRP3

Fig. 2

HucMSC-derived exosomes were successfully produced and endocytosed by HNPC. A Exosome markers CD63, CD9, and TSG101 proteins were detected by western blot in hucMSC-exo and hucMSC. B Internalization of exosomes by D-HNPC examined by laser scanning confocal microscope. Scale bar: 50 μm. Effect of hucMSC-exo depleted of exosomes on C cell viability, D m6A level, and E METTL14 expression in HNPC with or without 20 μM GW4869. ***P < 0.001

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