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Fig. 4 | Molecular Medicine

Fig. 4

From: Identifying FDA-approved drugs with multimodal properties against COVID-19 using a data-driven approach and a lung organoid model of SARS-CoV-2 entry

Fig. 4

Gene ontology analysis of the genes differentially regulated in A549 cells upon treatment with atorvastatin, based on transcriptomic data from the L1000 repository. Volcano plots show the GO terms enriched within the A downregulated and B upregulated genes after treatment with this drug. The Y axis shows significance in the āˆ’Ā log10 scale, and the X axis, the enrichment ratio for each GO term (represented as dots in the graph)

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Molecular Medicine

ISSN: 1528-3658