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Fig. 1 | Molecular Medicine

Fig. 1

From: G protein coupled estrogen receptor attenuates mechanical stress-mediated apoptosis of chondrocyte in osteoarthritis via suppression of Piezo1

Fig. 1

GPER is upregulated in chondrocytes exposed to mechanical stress after Piezo1 silencing. a Heatmap of differential gene expression values upon Piezo1 silencing in chondrocytes exposed to mechanical stress. b Disease and function analysis of differential gene expression values upon Piezo1 silencing in chondrocytes exposed to mechanical stress. c RT-qPCR analysis of GPER genes in Piezo1-silenced chondrocytes compared with non-silenced chondrocytes (n = 3). d Protein expression of GPER in Piezo1-silenced chondrocytes compared with non-silenced chondrocytes (n = 3). All data are presented in mean ± SD *P < 0.05, compared with non-silenced chondrocytes

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