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Fig. 2 | Molecular Medicine

Fig. 2

From: An mRNA assay system demonstrates proteasomal-specific degradation contributes to cardiomyopathic phospholamban null mutation

Fig. 2

Expression of PLN modified mRNAs in hESC and differentiated cardiomyocytes. A Immunofluorescence images of modPLN (top), modHA-PLN (middle) and modHA-L39X (bottom) modRNA transfected hESCs. PLN (green), HA (red), DAPI (blue) indicating co-localization of PLN and HA signal (right panel). B Immunofluorescence images of modHA-PLN (first panel), modHA-L39X (second panel), modHA-PLN-T2A-mCherry (third panel), modHA-L39-T2A-mCherry (fourth panel) modRNAs transfected cardiomyocytes and negative control (last panel). α-Actinin (violet), HA (green), mCherry (red), DAPI blue. Scale bars = 50 µm

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