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Fig. 3 | Molecular Medicine

Fig. 3

From: Pinocembrin ameliorates post-infarct heart failure through activation of Nrf2/HO-1 signaling pathway

Fig. 3

Pinocembrin alleviated post-infarct heart failure-induced ventricular remodeling. A pinocembrin decreased collagen deposition in infarct border zone, evidenced by the Masson staining; B pinocembrin reversed the heart failure-induced rarefaction of vascular endothelial growth factor receptor 2, demonstrating an amelioration of angiogenesis; C western blot results showed that pinocembrin improved apoptosis. N = 3 for quantified analysis of western blot. D Terminal-deoxynucleoitidyl Transferase-Mediated Nick-End Labeling (TUNEL) assay detected the apoptotic cardiomyocytes in infarct border zone or in the approximate region of apex cordis.*: p < 0.05; **: p < 0.01

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