Pinocembrin ameliorates post-infarct heart failure through activation of Nrf2/HO-1 signaling pathway

Table 1 The cardiac parameters obtained from M-mode echocardiogram

	Sham		Sham + Pino		HF		HF + Pino
	6w	8w	6w	8w	6w	8w	6w	8w
EF (%)	87.26 ± 2.37	85.18 ± 2.45	88.91 ± 2.73	84.87 ± 2.23	54.93 ± 2.06†	43.83 ± 1.27	52.22 ± 1.75	54.91 ± 2.27**
FS (%)	52.28 ± 3.06	49.79 ± 2.73	55.50 ± 3.84	50.13 ± 2.93	25.22 ± 1.19†	19.03 ± 0.65	23.58 ± 1.01	25.10 ± 1.37**
LVIDs (mm)	2.79 ± 0.26	2.83 ± 0.28	2.59 ± 0.32	3.07 ± 0.33	6.67 ± 0.33†	7.57 ± 0.24	6.45 ± 0.29	6.05 ± 0.30**
LVIDd (mm)	5.79 ± 0.21	5.57 ± 0.25	5.71 ± 0.24	6.06 ± 0.38	8.90 ± 0.39†	9.33 ± 0.23	8.41 ± 0.31	8.05 ± 0.29**
LVESV (ml)	0.064 ± 0.018	0.070 ± 0.024	0.057 ± 0.021	0.090 ± 0.022	0.74 ± 0.097†	0.99 ± 0.089	0.65 ± 0.071	0.55 ± 0.075**
LVEDV (ml)	0.47 ± 0.047	0.42 ± 0.053	0.45 ± 0.054	0.54 ± 0.082	1.59 ± 0.20†	1.73 ± 0.12	1.33 ± 0.12	1.18 ± 0.12**

EF left ventricular ejection fraction, FS fractional shortening, LVIDd left ventricular inner dimension at end-diastolic stage, LVIDs left ventricular inner dimension at end-systolic stage, LVESV left ventricular end-systolic volume, LVEDV left ventricular end-diastolic volume
†p < 0.01 vs. sham group at the same period; **p < 0.01 vs. HF group at the same period

ISSN: 1528-3658