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Fig. 7 | Molecular Medicine

Fig. 7

From: MiR-100 overexpression attenuates high fat diet induced weight gain, liver steatosis, hypertriglyceridemia and development of metabolic syndrome in mice

Fig. 7

MiR-100 mice demonstrate increased energy expenditure under high fat diet but not normal chow diet. ah At the end of the ND feeding period, the comprehensive laboratory animal monitoring system (CLAMS) measured ambulatory moving (a, e), heat generation (b, f), O2 consumption (c, g) and CO2 production (d, h). The graphs indicate the average during the day (ad) and night (ef). ip At the end of the HFD feeding period, the CLAMS measured ambulatory moving (I, m), heat generation (j, n), O2 consumption (k, o) and CO2 production (l, p). The graphs indicate the average during the day (il) and night (mp). (ND n = 5–6 and HFD n = 13) Data represent mean values with SEM. n.s. not significant, *P < 0.05 and ***P < 0.001 vs. the corresponding control

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