Fig. 6From: METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klothoMETTL14 promoted and α-klotho suppressed renal inflammation in db/db mice. A–C The levels of ROS, MDA, SOD in mice renal tissues, and D–F α-klotho, TNF-α and IL-6 in mice serum were detected by ELISA. Data are presented as the mean ± SD (n = 6); *P < 0.05, **P < 0.01 vs. db/m; #P < 0.05, ##P < 0.01 vs. db/db + rAAV; &P < 0.05, &&P < 0.01 vs. db/db + rAAV-METTL14Back to article page