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Fig. 6 | Molecular Medicine

Fig. 6

From: METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klotho

Fig. 6

METTL14 promoted and α-klotho suppressed renal inflammation in db/db mice. AC The levels of ROS, MDA, SOD in mice renal tissues, and DF α-klotho, TNF-α and IL-6 in mice serum were detected by ELISA. Data are presented as the mean ± SD (n = 6); *P < 0.05, **P < 0.01 vs. db/m; #P < 0.05, ##P < 0.01 vs. db/db + rAAV; &P < 0.05, &&P < 0.01 vs. db/db + rAAV-METTL14

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