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Fig. 1 | Molecular Medicine

Fig. 1

From: Depression of lncRNA MINCR antagonizes LPS-evoked acute injury and inflammatory response via miR-146b-5p and the TRAF6-NFkB signaling

Fig. 1

MINCR was upregulated in acute lung injury (ALI) mouse model and lipopolysaccharide (LPS)-injured alveolar epithelial cells. A the expression levels of MINCR in sepsis-induced ALI models. N = 10. B small airway epithelial cells (SAECs) were treated with different doses of LPS for 12 h, and then the expression level of MINCR was analyzed (N = 3). C after exposure to LPS for a specified period of time, the expression level of MINCR in SAECs was analyzed (N = 5). D hematoxylin and eosin staining (× 200) was used to observe the histological changes. Scale bar = 50 μm. E terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling staining was used to observe the histological changes (×200). Scale bar = 50 μm. *p < 0.05, **p < 0.01, ***p < 0.001 vs. Ctrl group; #p < 0.05 vs LPS. N = 10

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