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Fig. 3 | Molecular Medicine

Fig. 3

From: Depression of lncRNA MINCR antagonizes LPS-evoked acute injury and inflammatory response via miR-146b-5p and the TRAF6-NFkB signaling

Fig. 3

MiR-146b-5p directly regulated MINCR. A miR-146b-5p expression level in a model of acute lung injury (ALI) induced by lipopolysaccharide (LPS), N = 10. B MiR-146b-5p was predicted as a potential target of MINCR (C) miR-146b-5p expression level after mimic treatment. D analysis of luciferase activity in cells co-transfected with MINCR-wild type (WT) or MINCR-Mut vector. E immunoprecipitation test was used to determine the enrichment of MINCR and miR-146b-5p in the immunoprecipitation complex. Bars indicated standard deviation. *P < 0.05, **p < 0.01, N = 3

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Molecular Medicine

ISSN: 1528-3658