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Fig. 5 | Molecular Medicine

Fig. 5

From: Depression of lncRNA MINCR antagonizes LPS-evoked acute injury and inflammatory response via miR-146b-5p and the TRAF6-NFkB signaling

Fig. 5

MiR-146b-5p mediated the protective effect of sh-MINCR on lipopolysaccharide (LPS)-induced apoptosis and inflammation of small airway epithelial cells (SAECs). A cell viability was determined by CCK8. B apoptosis was detected by flow cytometry. C Caspase-3 activity assessment of different groups. D TNF (tumor necrosis factor)-α, IL (interleukin)-6 and IL-10 protein expression levels in SAECs was detected by Western blotting assay. *P < 0.05, **p < 0.01 vs. Ctrl group; #p < 0.05 vs. LPS group. N = 5

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Molecular Medicine

ISSN: 1528-3658