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Fig. 7 | Molecular Medicine

Fig. 7

From: Increased hemoglobin and heme in MALDI-TOF MS analysis induce ferroptosis and promote degeneration of herniated human nucleus pulposus

Fig. 7

Changes in the Notch signaling pathway in HNPCs after heme treatment. a Notch-related mRNAs in HNPCs were measured by qRT-PCR after 20 μg/mL heme treatment for 24 h with or without 30 μg/mL DFO pretreatment for 1 h. Data were analyzed with GraphPad Prism 5.02 software. *P < 0.05, **P < 0.01. b Notch-related proteins in HNPCs were measured by western blot analysis after 20 μg/mL heme treatment for 24 h with or without 30 μg/mL DFO pretreatment for 1 h

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