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Fig. 1 | Molecular Medicine

Fig. 1

From: Circular RNA-0007059 protects cell viability and reduces inflammation in a nephritis cell model by inhibiting microRNA-1278/SHP-1/STAT3 signaling

Fig. 1

Expression of circ_0007059 in kidneys, IFN-induced RMCs and HEK293 cells, and patients with lupus nephritis (LN). A microarray analysis revealed differentially expressed genes between kidney samples from patients with LN (n = 7) and normal healthy tissue (n = 7) (biological replicates, 7; technical replicates, 1; repeat time, 3). B the expression of circ_0007059 in renal biopsy samples from patients with LN (n = 30) and surrounding normal tissue samples (n = 10) by RT-qPCR (biological replicates, as indicated; technical replicates, 3; repeat time, 3). C, D treatment of RMCs and HEK293 cells with IFN (1,000 units/mL) for 24 h. RT-qPCR was used to measure the expression of circ_0007059 (biological replicates, 3; technical replicates, 2; repeat time, 3). Results are showed as the mean ± SEM for biological replicates. *P < 0.05 vs. the indicated group

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Molecular Medicine

ISSN: 1528-3658