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Table 1 Genomic information of 12 CpG sites for PDCD-1 and LAG-3 in GEO dataset

From: Inhibitory immune checkpoints PDCD-1 and LAG-3 hypermethylation may reduce the risk of colorectal cancer

Gene Symbol

CpG

Chromosome

Relation to island

P value

PDCD-1

cg09031938

chr2

Island

2.661E−04

cg03903296

chr2

Island

4.067E−07

cg06291111

chr2

Island

1.798E−07

cg07281781

chr2

Island

8.854E−05

cg10057601

chr2

Shore

3.169E−02

cg11532131

chr2

Shore

1.780E−02

cg04789125

chr2

Shore

5.368E−03

cg10994870

chr2

Island

5.111E−03

LAG-3

cg10191002

chr12

Island

3.961E−02

cg04153135

chr12

Shore

2.355E−02

cg06157570

chr12

Shelf

8.326E−03

cg14292870

chr12

Opensea

2.019E−03

  1. The final screened CpG sites were indicated in bold