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Fig. 1 | Molecular Medicine

Fig. 1

From: Calcitriol confers neuroprotective effects in traumatic brain injury by activating Nrf2 signaling through an autophagy-mediated mechanism

Fig. 1

The neuroprotective effects of calcitriol in TBI-induced neurological deficits and memory dysfunction. a The variation in neurological deficits at 14 days after treatment was determined by neurological severity score tests. b The time (seconds) spent finding the submerged platform at 14 days. c The time (seconds) spent on exploring the quadrant that initially contained the platform at 14 days. d Representative traces indicating the sample paths of the mice in the orientation navigation test. e Representative traces in the probe test indicating the sample paths of the mice after the platform was removed. Data are presented as means ± SEM (n = 10). *P < 0.05 and **P < 0.01 versus the indicated groups. (Sham: sham-operated group; TBI: TBI model group; Calcitriol: TBI + calcitriol treatment group)

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