Fig. 1
From: Overexpression of GINS4 is associated with poor prognosis and survival in glioma patients
The GINS4 was frequently upregulated in glioma. A Based on GEPIA2 database, the expression levels of GINS4 in various tumors were shown. On top labels, the color of the tumor name represents the level of GINS4 in the tumor compared with the corresponding normal tissues. Red indicates the high level of GINS4 in tumor tissue: Bladder Urothelial Carcinoma (BLCA), Breast invasive carcinoma (BRCA), Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), Colon adenocarcinoma (COAD), Lymphoid Neoplasm Diffuse Large B-cell Lymphoma (DLBC), Esophageal carcinoma (ESCA), Glioblastoma multiforme (GBM), Head and Neck squamous cell carcinoma (HNSC), Lung squamous cell carcinoma (LUSC), Ovarian serous cystadenocarcinoma (OV), Pancreatic adenocarcinoma (PAAD), Rectum adenocarcinoma (READ), Skin Cutaneous Melanoma (SKCM), Stomach adenocarcinoma (STAD), Testicular Germ Cell Tumors (TGCT), Thymoma (THYM), Uterine Corpus Endometrial Carcinoma (UCEC), and Uterine Carcinosarcoma (UCS); Green indicates the low level of GINS4 in tumor tissue: Acute Myeloid Leukemia (LAML); Black indicates that there is no significant difference between the level of tumor tissue and normal tissue: Adrenocortical carcinoma (ACC), Cholangio carcinoma (CHOL), Kidney Chromophobe (KICH), Kidney renal clear cell carcinoma (KIRC), Kidney renal papillary cell carcinoma (KIRP), Brain Lower Grade Glioma (LGG), Liver hepatocellular carcinoma (LIHC), Lung adenocarcinoma (LUAD), Mesothelioma (MESO), Pheochromocytoma and Paraganglioma (PCPG), Prostate adenocarcinoma (PRAD), Sarcoma (SARC), Thyroid carcinoma (THCA), Uveal Melanoma (UVM); B The expression level of GINS4 was compared between glioma cell lines and corresponding normal cell lines by RT-qPCR. C The expression level of GINS4 was compared between 17 glioma tissues and 10 corresponding normal brain tissues by RT-qPCR