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Fig. 9 | Molecular Medicine

Fig. 9

From: Deregulation of circ_003912 contributes to pathogenesis of erosive oral lichen planus by via sponging microRNA-123, -647 and -31 and upregulating FOXP3

Fig. 9

Transfection of circ_003912 siRNA influenced the levels of inflammatory cytokines and cell proliferation of THP-1 cells (*P value < 0.05 compared with NC group; student’s t-test). A transfection of circ_003912 siRNA increased the level of IL-4 in cell supernatants of THP-1 cells; B transfection of circ_003912 siRNA decreased the level of IFN-r in cell supernatants of THP-1 cells; C transfection of circ_003912 siRNA increased the level of IL-10 in cell supernatants of THP-1 cells; D transfection of circ_003912 siRNA decreased the level of IL-2 in cell supernatants of THP-1 cells; E transfection of circ_003912 siRNA decreased the proliferation of THP-1 cells

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