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Fig. 1 | Molecular Medicine

Fig. 1

From: Role of long non-coding RNA H19 in the development of osteoporosis

Fig. 1

Mechanisms of action of lncRNAs in bone development. LncRNA regulates osteogenic differentiation through Wnt/β-catenin and MAPK pathways. lncRNA ANCR and lncRNA HOTAIR affect the Wnt/β-catenin pathway and inhibit osteogenic differentiation. LncRNA DANCR and LncRNA SNHG1 regulate osteogenic differentiation through the MAPK pathway. LncRNA regulates osteoclast differentiation through RANK/RANKL/OPG and other pathways. LncRNA Bmncr inhibits RANKL-induced osteoclast differentiation

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Molecular Medicine

ISSN: 1528-3658