Table 1 Sample characteristics

Age, median [IQR]—yr

57.6 [48.5, 66.3]

53.8 [46.4, 63.8]

61.8 [55.3, 69.1]

0.0336^†

55.5 [48.3, 63.3]

64.4 [59.3, 74.9]

0.0059^†

Male sex – no. (%)

70 (63.1%)

40 (53.3%)

30 (83.3%)

0.0071^§

56 (62.9%)

14 (63.6%)

1^§

Hypertension (HTN)—no. (%)

38 (34.2%)

25 (33.3%)

13 (36.1%)

0.8324^§

28 (31.5%)

10 (45.5%)

0.2664^§

Coronary artery disease (CAD)—no. (%)

9 (8.1%)

3 (4%)

6 (16.7%)

0.0671^§

4 (4.5%)

5 (22.7%)

0.0249^§

Diabetes mellitus (DM) – no. (%)

22 (19.8%)

10 (13.3%)

12 (33.3%)

0.0336^§

13 (14.6%)

9 (40.9%)

0.0249^§

Chronic obstructive pulmonary disease (COPD)—no. (%)

0

0

0

/

0

0

/

Chronic kidney disease (CKD)—no. (%)

4 (3.6%)

1

3

/

3

1

/

Neoplasia—no. (%)

2 (1.8%)

2

0

/

2

0

/

PaO₂/FiO₂, median [IQR]

288.57, [201.67 367.6]

319.0 [271.4, 393.3]

195.2 [82.5, 271.3]

 < 0.0001^†

309.5 [228.6, 374.3]

201.7 [131.7, 276.8]

0.0059^†

NLR, median [IQR]

5.33, [3.3, 8]

4.4444 [2.9, 6.8]

7.7083 [5.4, 10.6]

0.0003^†

4.8231 [3.2, 7.5]

6.5 [5.4, 13.4]

0.0253^†

LDH, median [IQR]

374, [273.5, 522.25]

321 [241, 455]

503 [369, 675]

0.0001^†

334 [252, 483.5]

503 [369, 562]

0.0059^†

CRP, median [IQR]

85, [24.2, 152.8]

60.1 [9.1, 127.4]

132.5 [69.5, 235.7]

0.0001^†

76 [16.7, 142.7]

127.1 [57.6, 207.2]

0.0249^†

Creatinine, median [IQR]

0.89, [0.73, 1.12]

0.8 [0.72, 1]

0.985 [0.85, 1.3]

0.0105^†

0.82 [0.72, 1.01]

1.2 [0.92, 1.42]

0.0059^†

Time (Days) from symptom onset to blood draw, median [IQR]

8 [5; 11]

8 [4.5; 11]

8 [6; 10.25]

0.8324^†

9 [6; 11]

7 [2.25; 9]

0.0651^†

Time (Days) from hospital admission to blood draw, median [IQR]

1 [0; 2]

1 [0; 1]

1 [1; 2]

0.065^†

1 [0; 2]

1 [0; 2]

1^†

Transfer to ICU—no. (%)

36 [32.4%]

Death—no. (%)

22 [19.8%]

Time (Days) from hospital discharge to the follow-up sampling, median [IQR]

23 [20–40]

Total number of Leukocytes median [IQR]

7,2 [5.4–10.3]  × 10^9 /L

Total number of platelets median [IQR]

235 [165–329]

 × 10^9 /L