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Table 1 Sample characteristics

From: CXCL10 levels at hospital admission predict COVID-19 outcome: hierarchical assessment of 53 putative inflammatory biomarkers in an observational study

  Total Patients without ICU (n = 75) Patients with ICU (n = 36) p-value Alive (n = 89) Dead (n = 22) p-value
Age, median [IQR]—yr 57.6 [48.5, 66.3] 53.8 [46.4, 63.8] 61.8 [55.3, 69.1] 0.0336 55.5 [48.3, 63.3] 64.4 [59.3, 74.9] 0.0059
Male sex – no. (%) 70 (63.1%) 40 (53.3%) 30 (83.3%) 0.0071§ 56 (62.9%) 14 (63.6%) 1§
Hypertension (HTN)—no. (%) 38 (34.2%) 25 (33.3%) 13 (36.1%) 0.8324§ 28 (31.5%) 10 (45.5%) 0.2664§
Coronary artery disease (CAD)—no. (%) 9 (8.1%) 3 (4%) 6 (16.7%) 0.0671§ 4 (4.5%) 5 (22.7%) 0.0249§
Diabetes mellitus (DM) – no. (%) 22 (19.8%) 10 (13.3%) 12 (33.3%) 0.0336§ 13 (14.6%) 9 (40.9%) 0.0249§
Chronic obstructive pulmonary disease (COPD)—no. (%) 0 0 0 / 0 0 /
Chronic kidney disease (CKD)—no. (%) 4 (3.6%) 1 3 / 3 1 /
Neoplasia—no. (%) 2 (1.8%) 2 0 / 2 0 /
PaO2/FiO2, median [IQR] 288.57, [201.67 367.6] 319.0 [271.4, 393.3] 195.2 [82.5, 271.3]  < 0.0001 309.5 [228.6, 374.3] 201.7 [131.7, 276.8] 0.0059
NLR, median [IQR] 5.33, [3.3, 8] 4.4444 [2.9, 6.8] 7.7083 [5.4, 10.6] 0.0003 4.8231 [3.2, 7.5] 6.5 [5.4, 13.4] 0.0253
LDH, median [IQR] 374, [273.5, 522.25] 321 [241, 455] 503 [369, 675] 0.0001 334 [252, 483.5] 503 [369, 562] 0.0059
CRP, median [IQR] 85, [24.2, 152.8] 60.1 [9.1, 127.4] 132.5 [69.5, 235.7] 0.0001 76 [16.7, 142.7] 127.1 [57.6, 207.2] 0.0249
Creatinine, median [IQR] 0.89, [0.73, 1.12] 0.8 [0.72, 1] 0.985 [0.85, 1.3] 0.0105 0.82 [0.72, 1.01] 1.2 [0.92, 1.42] 0.0059
Time (Days) from symptom onset to blood draw, median [IQR] 8 [5; 11] 8 [4.5; 11] 8 [6; 10.25] 0.8324 9 [6; 11] 7 [2.25; 9] 0.0651
Time (Days) from hospital admission to blood draw, median [IQR] 1 [0; 2] 1 [0; 1] 1 [1; 2] 0.065 1 [0; 2] 1 [0; 2] 1
Transfer to ICU—no. (%) 36 [32.4%]       
Death—no. (%) 22 [19.8%]       
Time (Days) from hospital discharge to the follow-up sampling, median [IQR] 23 [20–40]       
Total number of Leukocytes median [IQR] 7,2 [5.4–10.3]  × 10^9 /L       
Total number of platelets median [IQR] 235 [165–329]
 × 10^9 /L
      
  1. Mann–Whitney test with false discovery rate (FDR) correction (Patients without ICU vs Patients with ICU; Alive vs Dead)
  2. §Fisher's test with false discovery rate (FDR) correction (Patients without ICU vs Patients with ICU; Alive vs Dead)
  3. IQR interquartile range
  4. NLR neutrophils to lymphocytes ratio
  5. LDH lactate dehydrogenase
  6. CRP C-reactive protein