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Fig. 3 | Molecular Medicine

Fig. 3

From: Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway

Fig. 3

HMSC-exos suppressed the proliferation of AML cells. A The uptake of HMSC-exos labeled with PKH-67 by human THP-1 cells was detected using immunofluorescence. B The proliferation of THP-1 cells co-cultured with HMSC-exos. C The protein level of TRIM14 in THP-1 cells after co-cultured with HMSC-exos. D Overexpression of TRIM14 suppressed the apoptosis of THP-1 cells after co-cultured with HMSC-exos. E The expression of TRIM14, cleaved caspase-3, AKT and p-AKT in the presence of oeTRIM14 and HMSC-exos. * p < 0.05; *** p < 0.001; !!!*** p < 0.001 vs oeNC

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Molecular Medicine

ISSN: 1528-3658