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Fig. 5 | Molecular Medicine

Fig. 5

From: Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway

Fig. 5

miR-23a-5p suppressed the expression of TRIM14 through binding on its 3’UTR in AML cells. A The level of miR-23b-5p and TRIM14 in THP-1 cells after the transfection of miR-23b-5p miNC, inhibitor and mimic. B The protein of TRIM14 was in THP-1 cells after the transfection of miR-23b-5p miNC, inhibitor and mimic. C The potential binding site of miR-23a-5p in the 3’UTR region of TRIM14. D The luciferase activity THP-1 cells after co-transfected with wildtype and mutant TRIM14 vectors as well as miR-23a-5p miNC, mimic and inhibitor. *** p < 0.001

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Molecular Medicine

ISSN: 1528-3658