Fig. 3From: Paediatric obesity: a systematic review and pathway mapping of metabolic alterations underlying early disease processesVisualisation of alterations in carbohydrate metabolism. Overview of altered carbohydrate metabolism and points of intersection with lipid and amino acid metabolism in childhood obesity. Black arrows indicate reactions, whilst red and blue arrows, respectively, indicate down- and upregulation of metabolites. Created with www.BioRender.com. G-6-P, glucose-6-phosphate; F-6-P, fructose-6-phosphate; BCAA, branched-chain amino acid; ROS reactive oxygen species; TG, triglyceride; LCFA, long-chain fatty acid; UA, uric acid; mTOR, mammalian target of rapamycinBack to article page