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Fig. 7 | Molecular Medicine

Fig. 7

From: Correction to: MicroRNA‑214 promotes alveolarization in neonatal rat models of bronchopulmonary dysplasia via the PlGF‑dependent STAT3 pathway

Fig. 7

miR-214 overexpression blocks the effect of the activated STAT3 pathway on bronchial embryonic pulmonary epithelial cells by inhibiting PlGF. A The ultrastructure of alveolar epithelial cells under TEM (×10,000). B Western blot analysis to quantify the expression of antiapoptotic proteins (Survivin and Bcl-2) and proapoptotic proteins (Bax, c-myc, and cleaved caspase-3) proteins in embryonic pulmonary epithelial cells. C Western blot analysis to quantify the expression of the epithelial cell marker E-cadherin and the fibrosis marker α-SMA in embryonic pulmonary epithelial cells. Data are summarized as mean ± standard deviation. *p < 0.05 vs. pulmonary epithelial cells transfected with miR-214 NC and PlGF NC. #p < 0.05 vs. pulmonary epithelial cells transfected with miR-214 NC and PlGF. Multiple comparisons were performed using one-way ANOVA, followed by Tukey’s post hoc test. Each experiment was repeated three times

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