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Fig. 3 | Molecular Medicine

Fig. 3

From: Increased plasma disequilibrium between pro- and anti-oxidants during the early phase resuscitation after cardiac arrest is associated with increased levels of oxidative stress end-products

Fig. 3

Increased prooxidant levels after CA. a Rate of Amplex Red oxidation in rat plasma is decreased at ROSC and substantially increased 2 h post-ROSC. b Rate of dihydroethidium oxidation shows an increasing trend at 2 h post-ROSC. c Xanthine oxidase activity is significantly decreased at ROSC but increases 2 h post-ROSC. d Rate of dihydroethidium oxidation is unchanged at 2 h post-ROSC as compared with control with the addition of the xanthine oxidase inhibitor febuxostat. e Total nitrate and nitrite concentration is significantly increased at 2 h post-ROSC. f Plasma iron concentration significantly decreased at 2 h post-ROSC. *p < 0.05, **p < 0.01, and ***p < 0.001; ROSC, return of spontaneous circulation

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Molecular Medicine

ISSN: 1528-3658