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Table 2 Topological parameters of key nodes

From: Weighted gene co-expression network-based approach to identify key genes associated with anthracycline-induced cardiotoxicity and construction of miRNA-transcription factor-gene regulatory network

Gene symbol Attribution Average shortest pathLength Betweenness centrality Closeness centrality Degree
Ccn2 Core gene 2.12179487 0.50864445 0.47129909 64
Ankrd23 Core gene 2.31410256 0.38657305 0.43213296 55
Tnfrsf12a Core gene 2.55769231 0.17317216 0.39097744 30
Scn3b Core gene 2.62179487 0.1790707 0.38141809 29
Mybpc2 Core gene 2.73717949 0.10746715 0.36533958 23
Ryr2 Core gene 2.81410256 0.06456454 0.35535308 14
Tcf12 TF 2.28205128 0.05201617 0.43820225 5
Ctcf TF 2.58974359 0.03352043 0.38613861 5
Spdef TF 2.21794872 0.04987317 0.45086705 5
Ebf1 TF 2.82051282 0.018577 0.35454545 4
Sp1 TF 2.32051282 0.02773417 0.43093923 4
Rcor1 TF 2.33333333 0.02424099 0.42857143 4
miR-124-3p miRNA 2.75641026 0.01849095 0.3627907 4
miR-195-5p miRNA 2.42307692 0.01558517 0.41269841 3
miR-146a-5p miRNA 2.67948718 0.01365674 0.37320574 3
miR-17-5p miRNA 2.92307692 0.01346221 0.34210526 3
miR-15b-5p miRNA 2.98717949 0.00362107 0.33476395 2
miR-424-5p miRNA 2.98717949 0.00362107 0.33476395 2
  1. TF transcription factor