Fig. 4

Functional annotation of FRGS. A Enrichment analysis of the differentially expressed genes between different groups in GO. B GSEA analysis showed inflammatory response, TNF-α, IFN-α, IFN-γ, IL-6 and IL-2 were depressed in high-risk patients. C Infiltrations of immune cells are assessed based on TCGA cohort. D CD4+ T cells and M1 macrophages were depressed in the high fibroblastic tumor