|
Tissue and endothelial damage/activation
|
|
Syndecan-1 (ng/mL)
|
880.3 (504.0–1387.9) (49)
|
1031.4 (669.7–1901.7) (35)
|
504.0 (316.0–819.8) (14)
|
0.002
|
|
Thrombomodulin (ng/mL)
|
4175.0 (3604.3–5550.9) (49)
|
4534.0 (3722.5–5858.4) (35)
|
3780.0 (3326.9–4514.3) (14)
|
0.070
|
|
Inflammation
|
|
IL-1β (pg/mL)↑
|
15.8% (3/19)
|
15.4% (2/13)
|
16.7% (1/6)
|
1.000
|
|
IL-2R (U/mL)
|
1065.5 (493.8–1536) (20)
|
1284.0 (670.0–1981.0) (13)
|
1052.0 (359.0–1111.0) (7)
|
0.183
|
|
IL-6 (pg/mL)
|
97.7 (12.6–179.0) (25)
|
139.3 (66.2–294.8) (16)
|
12.2 (6.1–33.8) (9)
|
< 0.001
|
|
IL-8 (pg/mL)
|
51.7 (12.1–93.3) (19)
|
79.3 (42.5–163.0) (13)
|
15.7 (9.4–23.4) (6)
|
0.005
|
|
IL-10 (pg/mL)
|
9.2 (2.5–20.7) (19)
|
16.5 (2.5–31.6) (13)
|
4.3 (2.5–14.8) (6)
|
0.179
|
|
TNFα (pg/mL)
|
9.5 (6.2–24.0) (17)
|
14.5 (2.1–30.5) (11)
|
7.6 (6.2–9.5) (6)
|
0.494
|
|
Hematologic
|
|
White blood cell count (× 109/L)
|
10.9 (7.6–17.7) (46)
|
12.2 (7.9–18.7) (34)
|
9.5 (6.7–11.1) (12)
|
0.133
|
|
Neutrophil count (× 109/L)
|
8.8 (6.1–16.5) (45)
|
11.3 (6.8–17.8) (34)
|
6.7 (5.1–8.7) (11)
|
0.039
|
|
Lymphocyte count (× 109/L)
|
0.5 (0.3–0.8) (47)
|
0.5 (0.3–0.7) (34)
|
1.0 (0.5–1.7) (13)
|
0.012
|
|
Red blood cell count (× 1012/L)↓
|
0.0% (0/46)
|
0.0% (0/34)
|
0.0% (0/12)
|
NA
|
|
Hemoglobin (g/L)↓
|
0.0% (0/47)
|
0.0% (0/34)
|
0.0% (0/13)
|
NA
|
|
Hematocrit (%)↓
|
0.0% (0/46)
|
0.0% (0/34)
|
0.0% (0/12)
|
NA
|
|
Platelet count (× 109/L)
|
112.5 (55.5–213.5) (46)
|
75.5 (43.3–141.5) (34)
|
238.5 (148.8–349.8) (12)
|
< 0.001
|
|
Biochemical
| |
|
Glucose (mmol/L)
|
9.9 (7.2–12.6) (45)
|
10.9 (8.4–14.5) (33)
|
7.8 (6.2–10.3) (12)
|
0.057
|
|
Total cholesterol (mmol/L)
|
3.1 (2.4–3.5) (46)
|
2.8 (2.3–3.5) (34)
|
3.3 (3.1–5.0) (12)
|
0.027
|
|
HsCRP (mg/L)
|
79.4 (49.0–186.9) (35)
|
126.9 (61.9–205.1) (25)
|
31.6 (7.2–76.6) (10)
|
< 0.001
|
|
High-sensitive cardiac troponin I (pg/mL)↑
|
68.9% (31/45)
|
75.0% (24/32)
|
53.8% (7/13)
|
0.301
|
|
Myoglobin (ng/mL)↑
|
48.9% (22/45)
|
59.4% (19/32)
|
23.1% (3/13)
|
0.027
|
|
AST (U/L)↑
|
40.0% (18/45)
|
41.2% (14/34)
|
36.4% (4/11)
|
1.000
|
|
LDH (U/L)↑
|
93.6% (44/47)
|
97.1% (33/34)
|
84.6% (11/13)
|
0.181
|
|
CK (U/L)↑
|
38.1% (8/21)
|
44.4% (8/18)
|
0.0% (0/3)
|
0.409
|
|
CK-MB (ng/mL)↑
|
28.9% (13/45)
|
37.5% (12/32)
|
7.7% (1/13)
|
0.102
|
|
NT-proBNP (pg/mL)↑
|
84.1% (37/44)
|
87.1% (27/31)
|
76.9% (10/13)
|
0.696
|
|
Ferritin (μg/L)↑
|
90.9% (10/11)
|
100.0% (6/6)
|
80.0% (4/5)
|
0.455
|
|
Coagulation
|
|
Prothrombin time (second)
|
15.9 (14.9–18.7) (45)
|
17.3 (15.7–21.0) (33)
|
14.2 (13.6–15.7) (12)
|
< 0.001
|
|
Prothrombin activity (%)
|
68.5 (51.8–78.0) (44)
|
59.0 (44.0–71.0) (33)
|
88.0 (71.0–95.0) (11)
|
< 0.001
|
|
INR (ratio)
|
1.3 (1.2–1.6) (44)
|
1.4 (1.2–1.8) (33)
|
1.1 (1.0–1.2) (11)
|
< 0.001
|
|
Fibrinogen (g/L)
|
3.9 (3.2–5.3) (45)
|
3.6 (2.8–5.5) (33)
|
4.5 (3.6–5.3) (12)
|
0.495
|
|
APTT (second)
|
42.6 (38.0–51.9) (45)
|
42.6 (38.5–54.4) (33)
|
41.6 (36.5–45.8) (12)
|
0.303
|
|
Thrombin time (second)
|
15.5 (14.7–16.8) (45)
|
15.5 (14.8–17.5) (33)
|
15.4 (14.6–16.0) (12)
|
0.470
|
|
D-dimer (μg/mL FEU)
|
7.1 (2.5–18.6) (44)
|
13.5 (3.9–21.0) (33)
|
2.4 (1.2–3.7) (11)
|
0.002
|
|
Fibrinogen degradation products (μg/mL)
|
54.7 (13.7–110.9) (19)
|
56.7 (17.0–150.0) (15)
|
8.0 (4.0–44.3) (4)
|
0.027
|
|
Antithrombin (%)
|
82.0 (69.0–90.0) (23)
|
82.0 (66.5–87.0) (17)
|
86.5 (70.8–96.5) (6)
|
0.392
|
|
Other
|
|
Procalcitonin (ng/mL)
|
0.34 (0.10–1.32) (22)
|
0.52 (0.28–3.12) (13)
|
0.12 (0.07–0.30) (9)
|
0.006
|
|
ESR (mm/H)↑
|
88.9% (8/9)
|
75.0% (3/4)
|
100.0% (5/5)
|
0.444
|
|
aPLs positive
|
50.0% (3/6)
|
50.0% (2/4)
|
50.0% (1/2)
|
1.000
|
