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Fig. 2 | Molecular Medicine

Fig. 2

From: LncRNA HCG18 upregulates TRAF4/TRAF5 to facilitate proliferation, migration and EMT of epithelial ovarian cancer by targeting miR-29a/b

Fig. 2

Effect of HCG18 knockdown on EOC cell proliferation, migration, invasion and EMT. A Screening of shRNA for the knockdown of HCG18 in EOC cells. B, C Effect of HCG18 knockdown on EOC cell proliferation as determined by MTT and colony formation assays. D Effect of HCG18 knockdown on EOC cell migration as determined by scratch wound healing assay. E Effect of HCG18 knockdown on EOC cell invasion as detected by Transwell assay. F, G Effect of HCG18 knockdown on expression of EMT markers as measured by qRT–PCR and Western blot. H, I Effect of HCG18 knockdown on the expression of EMT transcription factors as determined by qRT–PCR and Western blot. n = 3. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658