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Fig. 4 | Molecular Medicine

Fig. 4

From: LncRNA HCG18 upregulates TRAF4/TRAF5 to facilitate proliferation, migration and EMT of epithelial ovarian cancer by targeting miR-29a/b

Fig. 4

Expression of TRAF4/5 in vivo and in vitro. A The interaction of TRAF4/5 mRNA and miR-29a/b as determined by sequence analysis. B, C TRAF4/5 expression levels in EOC tissues (n = 30) and normal tissues (n = 30) as measured by qRT–PCR. (D-E) Expression levels of HCG18 in EOC cell lines and normal cell lines by qRT–PCR (n = 3). F, G miR-29a/b overexpression reduced TRAF4/5 expression in EOC cells, as determined by Western blot and qRT–PCR (n = 3). H The interaction of TRAF4/5 mRNA and miR-29a/b as determined by dual luciferase reporter assay (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658