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Fig. 7 | Molecular Medicine

Fig. 7

From: LncRNA HCG18 upregulates TRAF4/TRAF5 to facilitate proliferation, migration and EMT of epithelial ovarian cancer by targeting miR-29a/b

Fig. 7

Effect of HCG18 knockdown on the tumorigenicity of EOC cells in nude mice. CAOV3 cells infected with shHCG18 or shNC were subcutaneously injected into the right flank of nude mice. A–C HCG18 knockdown inhibited tumour size and weight. D Expression of Ki67 was decreased after silencing HCG18. Scale bar = 50 μm. E, F miR-29a/b was upregulated while TRAF4/5 was downregulated after silencing HCG18. n = 5. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658