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Table 1 Differentially expressed EMT-related candidate genes in Rab31 overexpressing and vector control cells identified by profiler PCR array analysis

From: Rab31-dependent regulation of transforming growth factor ß expression in breast cancer cells

Gene

Protein

Downregulated in Rab31 overexpressing CAMA-1 cells

 TGFB1

Transforming growth factor, beta 1

 TGFB2

Transforming growth factor, beta 2

 TIMP-1

Tissue inhibitor of metalloproteases 1

 BMP7

Bone morphogenetic protein 7

 WNT11

Wnt family member 11

Upregulated in Rab31 overexpressing CAMA-1 cells

 VCAN

Versican

 TFPI2

Tissue factor pathway inhibitor 2

 STEAP1

STEAP family member 1

 PLEK2

Pleckstrin 2

  1. The mRNA of the depicted genes was at least twofold differentially regulated in Rab31 overexpressing compared to vector control cells in two independent biological replicates applying the Human EMT RT2 Profiler PCR Array (Qiagen)