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Fig. 1 | Molecular Medicine

Fig. 1

From: Long non-coding RNA XIST: a novel oncogene in multiple cancers

Fig. 1

XIST mediates mechanisms involved in digestive system tumors. A XIST could promote the expression of EZH2 by targeting miR-101. B XIST could promote the expression of CDK6/JAK2/STAT3 by targeting miR-494. C XIST could promote the expression of CCND1 by targeting miR-129-5p. D XIST could promote the expression of MACC1 by targeting miR-497. E XIST could promote the expression of TGF-β1 by targeting miR-185. F XIST could promote the expression of JAK2 by targeting miR-337. G XIST could promote the expression of PXN by targeting miR-132. H XIST could promote the expression of MAPK1 by targeting miR-132-3p. I XIST could promote the expression of ZEB1 by targeting miR-200b-3p. J XIST could promote the expression of EZH2 by targeting miR-137. K XIST could promote the expression of WNT1 by targeting miR-34a. L XIST could promote the expression of NRP-2 by targeting miR-486b-5p. M XIST could promote the expression of HIF-1A by targeting miR-93-5p. N XIST could promote the expression of PAX5 by targeting miR-338-3p. O XIST could promote the expression of FOXK1 by targeting miR-497-5p. P XIST could promote the expression of SGK1 by targeting miR-124. Q XIST could promote the expression of ROR1 by targeting miR-30a-5p. R XIST could promote the expression of PKM2/PKM1 by targeting miR-137. S XIST could promote the expression of EGFR by targeting miR-133a. T XIST could promote the expression of iASPP by targeting miR-140/124. U XIST could promote the expression of YAP by targeting miR-34a. V XIST could promote the expression of ZEB1 by targeting miR-429. W XIST could promote the expression of TGF-β2 by targeting miR-141-3p. X XIST could promote the expression of Notch1 by targeting miR-137. Y XIST could promote the expression of PDK1 by targeting miR-139-5p. Z XIST could promote the expression of MAPK1 by targeting miR-194-5p

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