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Table 2 Main characteristics of the studies included in the review of digestive system tumors

From: Long non-coding RNA XIST: a novel oncogene in multiple cancers

Study Tumor types Sample size
(Normal: Tumor)
Detection Method P value TNM
(p value)
LNM
(p value)
DM
(p value)
OS
(p value)
References
Wu Esophageal cancer (127: 127) qRT-PCR p = 0.0092 p = 0.000 / / p = 0.005 Wu et al. 2017a)
Chen Esophageal cancer (78: 78) qRT-PCR p < 0.001 / / / / Chen et al. 2019a)
Wang Esophageal cancer (42: 42) qRT-PCR p < 0.001 p = 0.0064 / / p = 0.0039 Wang et al. 2021)
Chen Gastric cancer (106: 106) qRT-PCR p < 0.001 / / p = 0.033 p = 0.002 Chen et al. 2016)
Ma Gastric cancer (98: 98) qRT-PCR p < 0.05 p = 0.005 p = 0.002 / p < 0.05 Ma et al. 2017)
Li Gastric cancer (65: 65) qRT-PCR p < 0.05 / / / / Li et al. 2020b)
Li Gastric cancer (98: 98) qRT-PCR p < 0.05 p = 0.0077 p = 0.014 / / Li et al. 2020)
Zhang Colorectal cancer (196: 196) qRT-PCR p < 0.001 / / p < 0.001 p < 0.001 Zhang et al. 2019a)
Yu Colorectal cancer (41: 94) qRT-PCR p < 0.05 / / / p < 0.001 Yu et al. 2020)
Yang Colorectal cancer (37: 37) qRT-PCR p < 0.0001 / / p = 0.008 / Yang et al. 2020)
Song Colorectal cancer (50: 50) qRT-PCR p < 0.05 p = 0.034 / / / Song et al. 2017)
Chen Colorectal cancer (115: 115) qRT-PCR p < 0.05 / / / p = 0.01 Chen et al. 2017)
Liu Colorectal cancer (20: 20) qRT-PCR p < 0.001 / / / / Liu et al. 2018)
Sun Colorectal cancer (120: 120) qRT-PCR p < 0.01 p = 0.005 p = 0.035 p = 0.02 p < 0.05 Sun et al. 2018b)
Liu Colorectal cancer (317: 317) qRT-PCR p < 0.05 p = 0.04 p < 0.001 / p < 0.001 Liu et al. 2019)
Yang Colorectal cancer (36: 36) qRT-PCR p < 0.001 p = 0.0333 / / / Yang et al. 2020)
Li Colorectal cancer (30: 30) qRT-PCR p < 0.05 p = 0.028 / / / Li et al. 2021)
Wang Colorectal cancer (54: 54) qRT-PCR p < 0.01 / / / / Wang et al. 2020b)
Zhang Colorectal cancer (294: 294) qRT-PCR p < 0.05 / p = 0.037 / p < 0.001 Zhang et al. 2019c)
Sun Pancreatic cancer (139: 139) qRT-PCR p < 0.001 / / / p < 0.001 Sun et al. 2018a)
Wei Pancreatic cancer (64: 64) qRT-PCR p < 0.01 p = 0.023 / / p = 0.002 Wei et al. 2017)
Liang Pancreatic cancer (73: 73) qRT-PCR p < 0.01 / / / p = 0.003 Liang et al. 2017)
Shen Pancreatic cancer (120: 120) qRT-PCR p < 0.001 / / / / Shen et al. 2019)
Sun Pancreatic cancer (30: 30) qRT-PCR p < 0.01 / / / / Sun and Zhang 2019)
Liu Pancreatic cancer (40: 40) qRT-PCR p < 0.001 / / / / Liu et al. 2020)
Liu Hepatocellular carcinoma (55: 55) qRT-PCR p < 0.05 / / / / Liu and Xu 2019)
Dong Hepatocellular carcinoma (69: 69) qRT-PCR p < 0.001 / / / / Dong et al. 2020)
Mo Hepatocellular carcinoma (88: 88) qRT-PCR p < 0.05 / / / / Mo et al. 2017)
Kong Hepatocellular carcinoma (52: 52) qRT-PCR p < 0.05 / / / p < 0.05 Kong et al. 2018)