Skip to main content
Fig. 1 | Molecular Medicine

Fig. 1

From: Targeting CK2 mediated signaling to impair/tackle SARS-CoV-2 infection: a computational biology approach

Fig. 1

Sequence alignment of the nucleocapsid proteins of SARS-CoV-2 (NCAP_SARS2) and SARS-CoV (NCAP_CVHSA) viruses. Numbers at the right end indicate the amino acid position in the SARS-CoV-2 protein. Above the aligned sequences, the RNA-binding (residues 41–186, according to UniProt annotation) and Dimerization (residues 258–361) domains are delimited. The v-above the amino acid residues indicates the phosphorylation sites identified in the works of Davidson et al. (2020), Bouhaddou et al. (2020), Klann et al. (2020) and Hekman et al. (2020). The highlighted segments are those between a CK2 phospho-acceptor site and position + 3, those amino acids in yellow are the ones in silico predicted by Surjit et al. (2005) and in green are those experimentally validated by Davidson et al. (2020)

Back to article page