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Fig. 3 | Molecular Medicine

Fig. 3

From: Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway

Fig. 3

Pathological changes of DG area. A H&E staining of the hippocampus. In the SGZ of the WT + CIH group, NBs were hardly observed (White arrow), but SMND-309 treatment relieved the damage. Original magnification: 400×. B The TEM results of the hippocampus. Neurons of the WT + CIH group exhibited cytoplasmic vacuolization, LDs accumulation (black arrow) and mitochondrial disruption (black triangle). Moreover, glial cells of the WT + CIH group presented edema (black star), especially in the area surrounding the BBB. Original magnification: 15,000×. All experiments were repeated three times

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Molecular Medicine

ISSN: 1528-3658