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Fig. 8 | Molecular Medicine

Fig. 8

From: Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway

Fig. 8

CIH treatment did not significant influence the expression of PDP1/PDHA1 in hippocampus. A Nile Red staining of hippocampus. (Scale bar: 20 μm). B Quantification of LDs accumulation. C, D PDP1 and PDHA1 expression patterns were determined by RT-PCR. E–H Western blot assays were performed to determine the expression level of PDP1/PDHA1, and the gray value of the band was measured. I The PDC activity of hippocampus. J Total levels of acetyl-CoA in hippocampus. Each experiment was repeated three times. Data are shown as the mean ± SEM. Statistical analysis was performed with two-way ANOVA. *p < 0.05 WT group vs WT CIH group. Magnification: 400×. The local details are enlarged in the rectangular frame

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Molecular Medicine

ISSN: 1528-3658