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Fig. 9 | Molecular Medicine

Fig. 9

From: Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway

Fig. 9

ROS level and JNK/SREBP/ACC expression. A–G The ROS level was highly enhanced in the hippocampus of WT + CIH exposure (p < 0.05), and the JNK/SREBP/ACC pathway was activated. However, these changes were attenuated by SMND-309 treatment (p < 0.05). *p < 0.05 WT group vs. WT CIH group. **p < 0.05 WT CIH group vs. SMND-309 CIH group. All experiments were repeated three times. Data are expressed as the mean ± SEM. Statistical analysis was performed through two-way ANOVA

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Molecular Medicine

ISSN: 1528-3658