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Table 3 Effect of administration of QUE and/or MTX on paw volume

From: Quercetin mitigates rheumatoid arthritis by inhibiting adenosine deaminase in rats

Groups

Day (0)

Day (7)

Day (14)

Day (21)

Day (28)

Normal control

0.11 ± 0.009

0.133 ± 0.0045

0.137 ± 0.004

0.1331 ± 0.005

0.129 ± 0.003

Rheumatoid arthritis control

0.115 ± 0.004

1.032 ± 0.0078****

0.809 ± 0.013****

0.863 ± 0.024****

0.809 ± 0.013****

Methotrexate control

0.116 ± 0.006

0.13 ± 0.0058

0.102 ± 0.005

0.073 ± 0.002

0.070 ± 0.008

Quercetin control

0.122 ± 0.002

0.135 ± 0.0042

0.152 ± 0.002

0.132 ± 0.001

0.131 ± 0.001

Methotrexate treatment

0.127 ± 0.002

1.031 ± 0.0137****

0.898 ± 0.052****

0.408 ± 0.030+++,****

0.291 ± 0.029++++,**

Quercetin treatment

0.122 ± 0.002

1.026 ± 0.0096****

0.72 ± 0.032****

0.51 ± 0.048++,****

0.44 ± 0.030+++,***

Combination treatment

0.128 ± 0.002

1.032 ± 0.0079****

0.869 ± 0.016****

0.369 ± 0.016++++,***

0.233 ± 0.030++++,**

  1. p < 0.05 is considered significant, where +: significantly different from the RA control group and *: significantly different from the normal control groups. Results are expressed as mean ± SE, (n = 8)