Fig. 5

XIST overexpression attenuates adipose tissue histological changes in HFD-induced mice. A–D Tissue weight in male mice between groups. * vs CD + pCMV-CON, p < 0.05; # vs HFD + pCMV-CON, p < 0.05; $ vs CD + pCMV-CON, p < 0.05; & vs CD + pCMV-XIST p < 0.05; % vs CD + pCMV-CON, p < 0.05. E Representative HE stained subcutaneous and brown adipose tissue of male mice between groups. Scale bar, 50 μm