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Fig. 6 | Molecular Medicine

Fig. 6

From: Long noncoding RNA XIST regulates brown preadipocytes differentiation and combats high-fat diet induced obesity by targeting C/EBPα

Fig. 6

XIST overexpression effect on metabolism-related gene expression of adipose tissues in HFD-induced mice. A–D, F–I qRT-PCR analysis of XIST and indicated gene expression in sub-Q and BAT from male mice after intervention. *, p < 0.05. E, J Western blot analysis of indicated protein expression in sub-Q and BAT from male mice after intervention. CD, chow diet; HFD, high-fat diet; pCMV-CON, tail vein injection of control plasmid; pCMV-XIST, tail vein injection of XIST overexpression plasmid; BAT, brown adipose tissue; sub-Q, subcutaneous adipose tissue; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol. Data are represented as mean ± SEM

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Molecular Medicine

ISSN: 1528-3658