Fig. 1

Gene enriched pathways of L/R differential methylated regions. A DNA regions with more than 1% DM between L–R primary breast tumors from TCGA public dataset were analyzed by Metascape for enriched GO Biological processes (p value cut-off 0.001). B DNA regions with more than 10% DM between 6 L/R xenograft tumors were analyzed by Metascape for enriched GO Biological processes (p value cut-off 0.001). Ion/neural and embryonic pathways are highlighted in red