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Fig. 2 | Molecular Medicine

Fig. 2

From: Vascular hyperacetylation is associated with vascular smooth muscle dysfunction in a rat model of non-obese type 2 diabetes

Fig. 2

Increased arterial blood pressure, and impaired VSMC-dependent relaxation from GK rats in advanced T2DM. a Representative tracing of direct arterial blood pressure (BP) measurement via carotid catheterization. b Systolic BP (mmHg) and c Diastolic BP (mmHg). d Cumulative concentration–response curves to Sodium Nitroprusside (SNP) in aortas from GK rats (gray circles) in comparison to aortas from age-matched male Wistar rats (black circles). Each point represents the maximal response to each concentration of SNP, e Maximal relaxation response (Emax) to SNP, f pD2 for SNP curve. *p < 0.05 vs. control, n = 6 per group. Values are means ± SEM

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Molecular Medicine

ISSN: 1528-3658