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Fig. 3 | Molecular Medicine

Fig. 3

From: Gut bacterial metabolite Urolithin A inhibits myocardial fibrosis through activation of Nrf2 pathway in vitro and in vivo

Fig. 3

UA inhibited proliferation, migration and invasion of TGF-β1-stimulated CFs through activating Nrf2. A and C The mRNA level of Nrf2 in CFs after indicated treatments. B and D The protein level of Nrf2 in CFs after indicated treatments. β-actin was used as normalized control. E Cell viability was measured by MTT assay of CFs after indicated treatments. F Cell migration was measured by wound healing assay of CFs after indicated treatments. G Cell invasion ability was measured by transwell assay of CFs after indicated treatments. N = 3, *P < 0.05, **P < 0.01, ***P < 0.001

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