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Fig. 5 | Molecular Medicine

Fig. 5

From: Gut bacterial metabolite Urolithin A inhibits myocardial fibrosis through activation of Nrf2 pathway in vitro and in vivo

Fig. 5

UA treatment inhibited myocardial fibrosis via Nrf2 pathway in vivo. A Represent images by H&E staining of heart tissues from indicated groups and statistic score of injury level. B Represent images by Masson’s trichrome staining of heart tissues from indicated groups and statistic results of the fibrosis area. C The mRNA levels and D protein levels of fibrosis markers including vimentin, DDR2, tensin and α-SMA in heart tissues from indicated groups. E The protein levels of Nrf2, SOD1, HO-1 and NQO1 in heart tissues from indicated groups. β-actin was used as normalized control. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658