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Fig. 2 | Molecular Medicine

Fig. 2

From: Increased plasmablasts enhance T cell-mediated beta cell destruction and promote the development of type 1 diabetes

Fig. 2

The increase of plasmablasts correlates with the deterioration of beta cell function. AB Correlation between the number of plasmablasts and FCP (n = 35) and 2hCP (n = 32) in patients with new-onset T1D. C HbA1c levels in patients receiving MSC transplantation at baseline and 3 months after transplantation. DE Plasmablast number at baseline and 3 months after treatment in responders (D) and non-responders (E). FG Correlation between the altered plasmablast number and the change of FCP and 2hCP. Correlation was assessed by Pearson analysis. Difference between the data before and after MSC treatment were assessed by Paired t test. * P < 0.05. FCP, plasma fasting C-peptide; 2hCP, plasma 2-h postprandial C-peptide

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